Knee replacement timing is all wrong for most patients

The timing of knee replacement surgery is critical to optimize its benefit. But 90% of patients with knee osteoarthritis who would potentially benefit from knee replacement are waiting too long to have it and getting less benefit. In addition, about 25% of patients who don't need it are having it prematurely when the benefit is minimal, reports a new Northwestern Medicine study.

This is believed to be the first study to prospectively examine the timeliness of knee replacement among a large number of patients with knee osteoarthritis who could benefit from the surgery. Few prior studies have quantified timeliness of surgery but only among patients who already had knee replacement, and these studies generally were in smaller cohorts of patients.

"People are waiting and waiting to have the procedure and losing the most benefit," said lead investigator Hassan Ghomrawi, associate professor of surgery at Northwestern University Feinberg School of Medicine.

African-Americans delayed knee replacement surgery more than Caucasians, the study found.

"When people wait too long, two things happen," Ghomrawi said. "The osteoarthritis causes deterioration of their function. Some of them wouldn't be able to straighten out their legs, affecting their walking and mobility. When you can't get exercise, you can start to develop other health problems such as cardiovascular problems. You may also become depressed. The overall impact can be huge."